 Owen Wilson asked for privacy after being admitted to hospital |
The 39-year-old star will join Jennifer Aniston on 10 March to film Marley & Me for 20th Century Fox, a comedy revolving around a naughty dog.
Wilson dropped out of filming a cameo for this summer's Tropic Thunder and was replaced by Matthew McConaughey.
After being admitted to hospital last year, Wilson asked to be allowed "to heal in private".
Wilson's previous hits include Starsky and Hutch, You, Me and Dupree and The Wedding Crashers.
The latter film, which also starred Vince Vaughn and Isla Fisher, took around $285m (£146m) at the global box office in 2005.
He received an Oscar nomination in 2002 for scripting The Royal Tenenbaums with long-time collaborator Wes Anderson.
But, last year, Wilson had to drop out of the Venice premiere of Anderson's The Darjeeling Limited to recuperate at his home in Santa Monica, California.
Marley & Me, based on the bestselling book by John Grogan, is due out in the US on Christmas Day 2008.
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